The Solongevity Science

Muscles, sarcopenia

Why does strength diminuish with aging?

from 30 to 60 year old, about 7.5 kg of muscle mass is lost in favour of fat mass. This is a physiological phenomenon linked to ageing, which can become pathological. In this case we speak of sarcopenia. Muscle decline, however, can be prevented.

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cognitive ageing, cognitive reserve

Neuro-cognitive age: how the brain changes

Even the brain gets old. The loss of cognitive ability is linked to neurobiological changes, such as the thinning of the cerebral cortex. Today it is possible to measure this process and intervene both to slow it down and to recover what has been lost.

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dna damages, sirtuins

Time changes us, even in our DNA. That’s how

Along our lives, the genetic code contained in our cells accumulates small damages and the telomeres, the ends of the chromosomes, shorten, making it even less stable. Two phenomena linked to the ageing process and diseases of old age

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Immunesenescence

COVID-19, why are the elderly most affected?

As the immune system ages, it undergoes alterations and becomes less efficient. This is how processes such as immunosenescence and inflammaging affect it, exposing us to an increased risk of infection by pathogens such as the new coronavirus SARS-CoV-2.

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Immunesenescence, inflammaging

COVID-19, 5 rules to help prevent it

The elderly are more susceptible to infections such as coronavirus SARS-CoV-2 due to phenomena such as immunosenescence and inflammation. At their origin, however, there are epigenetic changes that we can influence through our lifestyle.

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inflammaging, longevity

The science of longevity: here’s what we know

115 years is the estimated intrinsic capacity of the human being to live. But how long we live, and how we live, does not depend solely on our genes. Epigenetic studies have shown that there are mechanisms that can repair DNA damage and increase longevity.

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dna, epigenetics

Why do we age? identified 9 biological causes

An international team of researchers has identified 9 “hallmarks”: key mechanisms of the ageing process of all organisms and many diseases such as cancer, diabetes, cardiovascular and neurodegenerative diseases. The role of Epigenetics is central

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